Hyperosmotic Laxative Precautions, Contraindications and Drug Interactions


These are general precautions about hyperosmotic laxatives.
     Please note: Follow your doctor's instructions if a laxative has been prescribed for you. If you have a concern about taking the laxative that has been ordered for you, talk with your doctor. If you are presently taking a laxative under orders from your doctor, talk with your doctor before discontinuing or reducing use of the laxative.


Contraindications Drug Interactions

Precautions

  • Consult with your doctor before using a hyperosmotic laxative.
  • If you notice a sudden change in bowel habits or function that lasts longer than 2 weeks, or keeps returning off and on, check with your doctor before using a hyperosmotic laxative.
  • Use only as directed. Do not administer more often than your doctor prescribed - even if you do not have results. Instead, contact your doctor.
  • Daily use of hyperosmotic laxatives is strongly discouraged.
  • Hyperosmotic laxatives are not to be taken for a period of time longer than one week unless directed by a doctor.
  • Do not use a hyperosmotic laxative if you have an allergy or sensitivity to its ingredients.
  • Rectal bleeding or failure to have a bowel movement after use of a hyperosmotic laxative may indicate a serious condition. Discontinue use and consult a physician.
  • Prolonged use can lead to tolerance. With continued use, the dose must be increased to induce the laxative effect.
  • Prolonged use can lead to dependence. With dependence, laxatives are required in order to move the bowel.
  • Long-term use of hyperosmotics can cause loss of electrolytes, in particular potassium.
  • Discontinue use in the event of diarrhea or watery stools unless directed by a doctor.
  • If large volumes of water are lost with the stool after taking a hyperosmotic laxative, drink at least six eight-ounce glasses of water per day to protect against dehydration.

Contraindications

  • Do not use hyperosmotic laxatives if you have missed a bowel movement for only 1 or 2 days unless directed by a doctor.
  • Do not use hyperosmotic laxatives when nausea, fever or vomiting is present unless directed by a doctor.
  • Do not use hyperosmotic laxatives if you have signs or symptoms of appendicitis or inflamed bowel (such as stomach or lower abdominal pain, cramping, bloating, soreness, nausea, or vomiting), renal function impairment, colostomy or ileostomy (increased risk of electrolyte or fluid imbalance), or when abdominal pain of unknown origin is present unless directed by a doctor.
  • Do not take a hyperosmotic laxative when diseases that can cause diarrhea are present, unless directed by a doctor.
  • Do not use a hyperosmotic if dehydrated, suffering from diarrhea or loose stools, unless directed by a doctor.
  • Individuals with congestive heart failure, hypertension, dehydration, or renal function impairment should not use hyperosmotic laxatives containing sodium, unless directed by a doctor. Saline laxatives may promote sodium retention resulting in edema, especially during pregnancy.

Drug Interactions

  • Specific Laxative and Prescription Drug Interactions.
  • If taking a prescription drug, consult with your doctor before taking a hyperosmotic laxative.
  • Magnesium containing hyperosmotics can interfere with anticoagulants, ciprofloxacin, digitalis glycosides, etidronate, and sodium polystyrene sulfonate.
  • Unless directed by a doctor, other medications should not be taken at the same time because they may be swept down the intestine before they are dissolved and absorbed.
  • Concomitant use of some drugs with hyperosmotic laxatives can increase the risk of fluid and potassium depletion leading to electrolyte imbalance.
  • The effectiveness of other medications may be inhibited due to drug interaction with the hyperosmotic laxative.
  • The effectiveness or the toxicity of other drugs may be intensified when hyperosmotic laxatives are overused

Data Gathering, Research & Reporting
by Carole Engel, Director Of Outreach
© 2004 Fruit-Eze™, Inc.
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